CROT

Across TCGA patient cohorts, CROT RNA expression is significantly associated with the protein abundance of many other proteins, with 14,062 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CROT-associated proteins across cancer lineages are TRIP6, SRI, and WASL. Each is linked with CROT in more than 4 cancer types. Because this analysis shows association rather than direction, both CROT-to-partner and partner-to-CROT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CROT versus TRIP6 in CCRCC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CROT→partner) and Y-score (partner→CROT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TRIP6 →	+0.305	+0.460	<.001	<.001	3	5
PDAC	SRI →	+0.457	+0.608	<.001	<.001	3	5
PDAC	WASL →	+0.459	+0.517	<.001	<.001	3	5
BRCA	CAVIN1_S127 →	+0.805	+0.893	<.001	<.001	3	4
GBM	COBLL1_S911 →	+0.608	+0.585	<.001	<.001	3	4
BRCA	DNMT1_S714 →	-0.495	-0.985	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,062 associations by consensus.

CROT vs TRIP6 — CCRCC

Explore this scatter interactively →