Across TCGA patient cohorts, CROCC2 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CROCC2-associated genes across cancer lineages are ATM, Cyclin-E2, and 14-3-3_beta. Each is linked with CROCC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CROCC2-to-partner and partner-to-CROCC2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CROCC2→partner) and Y-score (partner→CROCC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.774	-3.584	<.001	.002	3	2
UCEC	Cyclin-E2 →	+0.205	+2.459	.011	.020	3	2
UCEC	14-3-3_beta →	-0.107	-2.973	.027	.035	3	1
UCEC	Ku80 →	+0.298	+2.820	.008	.035	3	1
UCEC	PI3K-p85 →	-0.326	-2.459	.001	.020	3	1
UCEC	Annexin-1 →	+0.712	+3.189	.005	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

CROCC2 survival (RNA) · tumor vs normal (RNA) · all CROCC2 data types