CROCC

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CROCC RNA expression is significantly associated with the protein abundance of many other proteins, with 12,888 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CROCC-associated proteins across cancer lineages are RPS6KA5, CROCC_S483, and CROCC_S494. Each is linked with CROCC in more than 3 cancer types. Because this analysis shows association rather than direction, both CROCC-to-partner and partner-to-CROCC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CROCC versus RPS6KA5 in LSCC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CROCC→partner) and Y-score (partner→CROCC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCRPS6KA5 →+0.370+0.645.002.00134
OVCROCC_S483 →+1.425+1.308<.001.00234
LSCCCROCC_S494 →+0.554+0.674<.001<.00134
LSCCCROCC_S512 →+0.781+0.600<.001<.00134
CCRCCMATN2 →+0.679+0.478<.001<.00134
OVAPBB2 →+0.355+0.987<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,888 associations by consensus.

CROCC vs RPS6KA5 — LSCC

Per-sample scatter of CROCC vs RPS6KA5 in LSCC (Pearson r = 0.36).

Explore this scatter interactively →

Exploration