CRNN

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CRNN protein abundance is significantly associated with the RNA expression of many other genes, with 1,284 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CRNN-associated genes across cancer lineages are ZNF750, SPRR3, and TNS4. Each is linked with CRNN in more than 2 cancer types. Because this analysis shows association rather than direction, both CRNN-to-partner and partner-to-CRNN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRNN versus ZNF750 in UCEC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRNN→partner) and Y-score (partner→CRNN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECZNF750 →+1.569+1.630.002.00133
UCECSPRR3 →+3.940+2.214.003<.00133
UCECTNS4 →+2.336+1.792<.001.00232
UCECANKRD29 →+1.445+1.512.004.00532
UCECSPRR1B →+3.794+2.037.007<.00132
UCECSPRR1A →+3.612+2.274<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,284 associations by consensus.

CRNN vs ZNF750 — UCEC

Per-sample scatter of CRNN vs ZNF750 in UCEC (Pearson r = 0.51).

Explore this scatter interactively →

Exploration