CRMP1

Across TCGA pan-cancer cohorts, CRMP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CRMP1 data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CRMP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CRMP1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

UCEC, LUAD, and CCRCC are the cancer types where CRMP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	0.433	1.000	.007	48	view →
LUAD	DFS	Median	All	0.846	0.985	.002	34	view →
CCRCC	OS	Quartile	All	0.959	0.760	.013	11	view →
PDAC	OS	Quartile	III,IV	0.198	0.923	.004	6	view →
GBM	DFS	Tertile	All	0.805	0.651	.036	2	view →
LSCC	DFS	Tertile	All	0.965	0.922	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CRMP1–UCEC (OS)

Open the UCEC breakdown →