CRMP1

Across TCGA pan-cancer cohorts, CRMP1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of CRMP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CRMP1 RNA is repressed in tumor relative to normal tissue. In most cancer types CRMP1 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KICH, HNSC, and UCEC are the cancer types where CRMP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CRMP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−1.980	<.001	8	view →
HNSC	Male	IV	+1.856	<.001	8	view →
UCEC	All	All	−1.789	<.001	6	view →
LIHC	Female	All	+1.346	<.001	6	view →
LUAD	Female	All	−0.533	.001	4	view →
BRCA	All	II,III,IV	−0.410	<.001	4	view →
CHOL	Female	All	+4.420	<.001	3	view →
BLCA	Male	IV	−1.702	<.001	2	view →
READ	All	III,IV	+0.605	.009	2	view →
THCA	Female	All	−0.228	.026	2	view →
READ	Female	All	−1.046	.029	1	view →
KIRP	All	All	+0.566	.014	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

CRMP1–KICH

Open the KICH breakdown →