CRMP1

Across TCGA patient cohorts, CRMP1 mutation is significantly associated with the RNA expression of many other genes, with 2,914 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CRMP1-associated genes across cancer lineages are CCNA2, UHRF1, and CHAF1A. Each is linked with CRMP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CRMP1-to-partner and partner-to-CRMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCNA2 grouped by CRMP1-low versus CRMP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRMP1→partner) and Y-score (partner→CRMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCNA2 →	+0.578	+1.595	.008	.006	3	4
SKCM	UHRF1 →	+0.784	+3.182	.005	.009	3	4
SKCM	CHAF1A →	+0.629	+3.360	.001	.004	3	4
UCEC	ORC6 →	+0.485	+1.595	.004	.006	3	4
CESC	CDKN2AIPNLP2 →	+0.093	+5.306	<.001	.006	3	3
COAD	RNU6-177P →	+0.316	+3.502	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,914 associations by consensus.

CCNA2 by CRMP1 expression — UCEC

Explore this box plot interactively →