CRMP1

Across TCGA patient cohorts, CRMP1 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CRMP1-associated genes across cancer lineages are P-Cadherin, Bcl-xL, and PR. Each is linked with CRMP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRMP1-to-partner and partner-to-CRMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, P-Cadherin grouped by CRMP1-low versus CRMP1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRMP1→partner) and Y-score (partner→CRMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	P-Cadherin →	+0.251	+2.816	.045	.036	3	2
LUSC	Bcl-xL →	+0.178	+2.816	.037	.036	3	2
SKCM	PR →	-0.103	-2.321	.022	.035	3	2
SKCM	Chk1 →	+0.325	+3.334	<.001	.005	3	2
COAD	eIF4E →	+0.160	+2.597	.015	.005	3	2
COAD	ERK2 →	+0.219	+2.347	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

P-Cadherin by CRMP1 expression — LUSC

Explore this box plot interactively →