CRMP1

Across TCGA cell cohorts, CRMP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,453 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CRMP1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of cilium assembly, and Mitotic cytokinesis. Each is linked with CRMP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both CRMP1-to-partner and partner-to-CRMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by CRMP1-low versus CRMP1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRMP1→partner) and Y-score (partner→CRMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.148	+1.931	<.001	<.001	3	11
OESOPHAGUS	Regulation of cilium assembly →	+0.090	+2.474	.001	<.001	3	11
LUNG_SCLC	Mitotic cytokinesis →	+0.090	+2.027	<.001	.002	3	11
OESOPHAGUS	Nucleoside triphosphate metabolic process →	+0.088	+1.711	<.001	<.001	3	11
OESOPHAGUS	Regulation of base-excision repair →	+0.106	+1.666	.002	.002	3	10
BONE	Atrial cardiac muscle cell differentiation →	-1.010	-2.545	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,453 associations by consensus.

Negative regulation of myoblast fusion by CRMP1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →