CRLS1

Across TCGA patient cohorts, CRLS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,870 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRLS1-associated proteins across cancer lineages are TRMT6, TRMT61A, and MAVS. Each is linked with CRLS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CRLS1-to-partner and partner-to-CRLS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRLS1 versus TRMT6 in PDAC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRLS1→partner) and Y-score (partner→CRLS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TRMT6 →	+0.309	+0.288	<.001	.002	3	5
COAD	TRMT61A →	+0.375	+0.514	<.001	<.001	3	4
COAD	MAVS →	+0.278	+0.475	.001	<.001	3	4
HNSC	MTSS1 →	-0.592	-0.664	<.001	<.001	3	3
HNSC	NRBF2 →	-0.381	-0.685	.001	<.001	3	3
GBM	PTPRA →	+0.536	+0.475	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,870 associations by consensus.

CRLS1 vs TRMT6 — PDAC

Explore this scatter interactively →