CRLS1

Across TCGA patient cohorts, CRLS1 protein abundance is significantly associated with the RNA expression of many other genes, with 527 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CRLS1-associated genes across cancer lineages are TOM1, ZMYND8, and NUTF2. Each is linked with CRLS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRLS1-to-partner and partner-to-CRLS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRLS1 versus TOM1 in CCRCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRLS1→partner) and Y-score (partner→CRLS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TOM1 →	+0.492	+0.384	<.001	.009	3	1
CCRCC	ZMYND8 →	+0.700	+0.460	.009	.001	3	1
CCRCC	NUTF2 →	+0.416	+0.515	.005	.001	3	1
CCRCC	PRSS54 →	+0.107	+0.424	.005	.003	3	1
CCRCC	PSMD7 →	+0.532	+0.752	.001	<.001	3	1
CCRCC	VAC14 →	+0.572	+0.403	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 527 associations by consensus.

CRLS1 vs TOM1 — CCRCC

Explore this scatter interactively →