CRISP3

Across TCGA patient cohorts, CRISP3 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CRISP3-associated genes across cancer lineages are Endothelial cells, mv Endothelial cells, and Myocytes. Each is linked with CRISP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRISP3-to-partner and partner-to-CRISP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by CRISP3-low versus CRISP3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRISP3→partner) and Y-score (partner→CRISP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Endothelial cells →	-0.039	-3.675	.006	.001	3	1
SKCM	mv Endothelial cells →	-0.022	-1.841	.025	.008	3	1
SKCM	Myocytes →	+0.033	+2.047	.014	.016	3	1
SKCM	Basophils →	+0.138	+2.756	.012	<.001	3	1
LUAD	CLP →	+0.081	+2.833	.030	.035	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Endothelial cells by CRISP3 expression — SKCM

Explore this box plot interactively →