CRISP3

Across TCGA cell cohorts, CRISP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,273 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CRISP3-associated GO terms across cancer lineages are Chemokine (C-C motif) ligand 21 signaling pathway, Skeletal muscle fiber development, and Foam cell differentiation. Each is linked with CRISP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CRISP3-to-partner and partner-to-CRISP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chemokine (C-C motif) ligand 21 signaling pathway grouped by CRISP3-low versus CRISP3-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRISP3→partner) and Y-score (partner→CRISP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Chemokine (C-C motif) ligand 21 signaling pathway →	-0.108	-1.617	.002	.002	3	5
BREAST	Skeletal muscle fiber development →	-0.082	-1.741	.009	.001	3	5
BREAST	Foam cell differentiation →	-0.326	-1.864	.002	<.001	3	5
LUNG_SCLC	Purine nucleoside monophosphate biosynthetic process →	-0.076	-0.856	.009	.009	3	5
LUNG_NSCLC_LUAD	Neuroblast division in subventricular zone →	-0.102	-1.073	<.001	.008	3	4
BREAST	Morula formation →	+0.977	+2.510	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,273 associations by consensus.

Chemokine (C-C motif) ligand 21 signaling pathway by CRISP3 expression — BREAST

Explore this box plot interactively →