CRISP1

Across TCGA patient cohorts, CRISP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,371 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CRISP1-associated GO terms across cancer lineages are Endosome organization, Establishment of protein localization to membrane, and Response to alcohol. Each is linked with CRISP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both CRISP1-to-partner and partner-to-CRISP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosome organization grouped by CRISP1-low versus CRISP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRISP1→partner) and Y-score (partner→CRISP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Endosome organization →	+0.076	+0.113	<.001	<.001	3	11
STAD	Establishment of protein localization to membrane →	+0.072	+0.102	<.001	<.001	3	10
STAD	Response to alcohol →	+0.046	+0.091	<.001	<.001	3	9
STAD	Regulation of cell morphogenesis →	+0.052	+0.095	<.001	<.001	3	9
STAD	Regulation of protein ubiquitination →	+0.073	+0.117	<.001	<.001	3	9
ESCA	Obsolete cellular response to extracellular stimulus →	+0.071	+0.191	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,371 associations by consensus.

Endosome organization by CRISP1 expression — STAD

Explore this box plot interactively →