CRISP1

Across TCGA cell cohorts, CRISP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 97 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CRISP1-associated GO terms across cancer lineages are Organic acid catabolic process, Carboxylic acid catabolic process, and Cellular detoxification of nitrogen compound. Each is linked with CRISP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CRISP1-to-partner and partner-to-CRISP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organic acid catabolic process grouped by CRISP1-low versus CRISP1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRISP1→partner) and Y-score (partner→CRISP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Organic acid catabolic process →	+0.057	+0.045	<.001	.009	3	3
BREAST	Carboxylic acid catabolic process →	+0.057	+0.045	<.001	.009	3	3
BREAST	Cellular detoxification of nitrogen compound →	+0.171	+0.071	<.001	.009	3	2
BREAST	Adenylate cyclase-activating serotonin receptor signaling pathway →	+0.147	+0.052	.001	.008	3	2
BREAST	Serotonin receptor signaling pathway →	+0.190	+0.049	.001	.001	3	2
BREAST	Tertiary alcohol biosynthetic process →	+0.999	+0.049	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 97 associations by consensus.

Organic acid catabolic process by CRISP1 expression — BREAST

Explore this box plot interactively →