CRIM1-DT

Across TCGA pan-cancer cohorts, CRIM1-DT RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated CRIM1-DT data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CRIM1-DT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CRIM1-DT expression acts as an unfavorable survival marker, although some lineages such as UCS and THCA show a favorable association.

LUAD, UCS, and UCEC are the cancer types where CRIM1-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	II,III,IV	0.401	0.657	<.001	72	view →
UCS	DFS	Median	III,IV	0.422	0.142	.014	38	view →
UCEC	OS	Median	II,III,IV	0.280	0.751	.004	34	view →
HNSC	DFS	Tertile	All	0.247	0.443	<.001	25	view →
THCA	DFS	Median	IV	1.000	0.525	.002	19	view →
LUSC	OS	Tertile	All	0.729	0.599	.003	19	view →
LIHC	DFS	Quartile	III,IV	0.471	0.225	.010	13	view →
LGG	OS	Tertile	All	0.927	0.846	.001	10	view →
STAD	OS	Quartile	All	0.532	0.690	.014	9	view →
DLBC	OS	Median	All	1.000	0.813	.009	9	view →
CESC	OS	Median	II,III,IV	0.670	0.390	.041	8	view →
MESO	OS	Quartile	All	0.853	0.326	.006	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

CRIM1-DT–LUAD (DFS)

Open the LUAD breakdown →