CREM

Across TCGA patient cohorts, CREM protein abundance is significantly associated with the protein abundance of many other proteins, with 8,687 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CREM-associated proteins across cancer lineages are CAMK1_S363, BOD1L1_S2203, and CD151. Each is linked with CREM in more than 2 cancer types. Because this analysis shows association rather than direction, both CREM-to-partner and partner-to-CREM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CREM versus CAMK1_S363 in LSCC, with a Pearson correlation of -0.47.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CREM→partner) and Y-score (partner→CREM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CAMK1_S363 →	-0.640	-0.477	<.001	.002	3	2
GBM	BOD1L1_S2203 →	+0.691	+1.076	<.001	<.001	3	2
BRCA	CD151 →	-1.030	-0.543	<.001	<.001	3	2
GBM	COBLL1_S356 →	-0.938	-0.771	<.001	<.001	3	2
LUAD	AKAP8L_S552 →	+0.893	+0.522	<.001	<.001	3	2
BRCA	ARFIP1_S39 →	-1.096	-0.576	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,687 associations by consensus.

CREM vs CAMK1_S363 — LSCC

Explore this scatter interactively →