CREG1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CREG1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,534 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CREG1-associated genes across cancer lineages are HMOX1, NPL, and PELATON. Each is linked with CREG1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CREG1-to-partner and partner-to-CREG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CREG1 versus HMOX1 in GBM, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CREG1→partner) and Y-score (partner→CREG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMHMOX1 →+0.919+0.343<.001<.00135
UCECNPL →+1.000+0.657<.001<.00135
GBMPELATON →+0.679+0.484.001<.00135
GBMSIGLEC8 →+1.185+0.470.001<.00134
GBMCD33 →+0.689+0.426<.001<.00134
CCRCCPKD2L1 →+0.871+0.322<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,534 associations by consensus.

CREG1 vs HMOX1 — GBM

Per-sample scatter of CREG1 vs HMOX1 in GBM (Pearson r = 0.38).

Explore this scatter interactively →

Exploration