CREG1

Across TCGA cell cohorts, CREG1 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CREG1-associated genes across cancer lineages are OR4E2, GHSR, and SLURP1. Each is linked with CREG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CREG1-to-partner and partner-to-CREG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4E2 grouped by CREG1-low versus CREG1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CREG1→partner) and Y-score (partner→CREG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR4E2 →	+0.653	+3.289	<.001	.009	3	2
BLOOD_Leukemia	GHSR →	+0.017	+3.289	<.001	.009	3	1
BLOOD_Leukemia	SLURP1 →	+0.076	+3.289	<.001	.009	3	1
BLOOD_Leukemia	NXPH2 →	+0.024	+3.289	.002	.009	3	1
BLOOD_Leukemia	FERD3L →	+0.026	+3.969	<.001	.009	3	1
BLOOD_Leukemia	DEFB103A →	+0.018	+3.969	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

OR4E2 by CREG1 expression — BLOOD_Leukemia

Explore this box plot interactively →