CREBRF

Across TCGA pan-cancer cohorts, CREBRF mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CREBRF data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CREBRF mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CREBRF expression acts as an unfavorable survival marker.

PDAC, LUAD, and GBM are the cancer types where CREBRF mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	III,IV	0.486	1.000	.013	5	view →
LUAD	DFS	Tertile	II,III,IV	0.672	0.913	.036	5	view →
GBM	DFS	Median	All	0.630	0.797	.020	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CREBRF–PDAC (DFS)

Open the PDAC breakdown →