CREBRF

Across TCGA patient cohorts, CREBRF protein abundance is significantly associated with the RNA expression of many other genes, with 10,664 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CREBRF-associated genes across cancer lineages are CYBRD1, MRPL19, and NEIL3. Each is linked with CREBRF in more than 4 cancer types. Because this analysis shows association rather than direction, both CREBRF-to-partner and partner-to-CREBRF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CREBRF versus CYBRD1 in HNSC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CREBRF→partner) and Y-score (partner→CREBRF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CYBRD1 →	+1.766	+1.043	<.001	<.001	3	5
LSCC	MRPL19 →	-0.725	-0.460	<.001	<.001	3	4
LUAD	NEIL3 →	-0.901	-0.278	.002	<.001	3	4
BRCA	CENPE →	-0.947	-0.488	<.001	<.001	3	4
GBM	PLK4 →	-0.703	-0.472	.007	.001	3	4
BRCA	SUV39H2 →	-0.622	-0.412	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,664 associations by consensus.

CREBRF vs CYBRD1 — HNSC

Explore this scatter interactively →