CREB3L4

Across TCGA patient cohorts, CREB3L4 mutation is significantly associated with the RNA expression of many other genes, with 226 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CREB3L4-associated genes across cancer lineages are RNU6-796P, CBLL2, and RNU6-13P. Each is linked with CREB3L4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CREB3L4-to-partner and partner-to-CREB3L4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-796P grouped by CREB3L4-low versus CREB3L4-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CREB3L4→partner) and Y-score (partner→CREB3L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-796P →	+0.344	+4.548	<.001	.009	3	2
UCEC	CBLL2 →	+0.111	+3.182	.008	<.001	3	2
UCEC	RNU6-13P →	+0.375	+2.800	<.001	.007	3	2
UCEC	RNA5SP280 →	+0.274	+3.077	.001	.009	3	2
UCEC	LINC02794 →	+0.071	+2.868	.005	.006	3	2
UCEC	MIR5689HG →	+0.318	+2.774	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 226 associations by consensus.

RNU6-796P by CREB3L4 expression — LUSC

Explore this box plot interactively →