Q-omics provides the consensus-scored MIR5689HG profile across patient tissues and cancer cell-line models. MIR5689HG expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, MIR5689HG is differentially expressed in 10, with the highest sampling consensus in KIRC. Additionally, MIR5689HG RNA expression shows 12,061 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight KIRC, and TGCT as cancer lineages where MIR5689HG shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR5689HG — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR5689HG survival associations across molecular data types. MIR5689HG RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR5689HG RNA expression–survival associations across cancer types. High MIR5689HG expression shows unfavorable associations in KIRC, PAAD, LUAD, ACC and MESO, but favorable associations in UVM. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for MIR5689HG RNA expression.
This table summarizes MIR5689HG tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR5689HG. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR5689HG shows lower tumor expression in KIRC and higher tumor expression in HNSC, BLCA, LUAD, LUSC and KIRP. The KIRC box plot shows higher MIR5689HG RNA expression in normal versus tumor tissue (log2 FC = −0.047, t-test p < 0.001).
This table shows molecular features associated with MIR5689HG in patient tissues and cancer cell lines. In patient samples, MIR5689HG shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
