CREB3L3

Across TCGA patient cohorts, CREB3L3 protein abundance is significantly associated with the RNA expression of many other genes, with 320 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CREB3L3-associated genes across cancer lineages are ANKRD26, HGFAC, and KHDRBS2. Each is linked with CREB3L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CREB3L3-to-partner and partner-to-CREB3L3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CREB3L3 versus ANKRD26 in UCEC, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CREB3L3→partner) and Y-score (partner→CREB3L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ANKRD26 →	+0.696	+0.923	.009	.006	3	1
UCEC	HGFAC →	+1.630	+0.923	<.001	.006	3	1
UCEC	KHDRBS2 →	-0.919	-0.923	.009	.006	3	1
UCEC	NPR3 →	-2.289	-0.923	<.001	.006	3	1
UCEC	NUDCD1 →	+0.586	+0.923	.001	.006	3	1
UCEC	EFNB2 →	-1.180	-0.923	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 320 associations by consensus.

CREB3L3 vs ANKRD26 — UCEC

Explore this scatter interactively →