CREB3L3

Across TCGA cell cohorts, CREB3L3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,164 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CREB3L3-associated GO terms across cancer lineages are Organophosphate ester transport, Protein depolymerization, and Protein K48-linked ubiquitination. Each is linked with CREB3L3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CREB3L3-to-partner and partner-to-CREB3L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organophosphate ester transport grouped by CREB3L3-low versus CREB3L3-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CREB3L3→partner) and Y-score (partner→CREB3L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Organophosphate ester transport →	+0.026	+0.623	.007	.006	3	5
LUNG_NSCLC_LUAD	Protein depolymerization →	+0.053	+0.350	.002	.005	3	5
UPPER_AERODIGESTIVE_TRACT	Protein K48-linked ubiquitination →	+0.081	+0.060	<.001	.001	3	5
STOMACH	Glycosphingolipid biosynthetic process →	+0.060	+1.400	<.001	.004	3	5
BLOOD_Leukemia	Positive regulation of mitotic cytokinesis →	+0.108	+1.503	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Regulation of apoptotic signaling pathway →	+0.060	+0.052	.002	.008	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,164 associations by consensus.

Organophosphate ester transport by CREB3L3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →