CREB3L2

Across TCGA patient cohorts, CREB3L2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,474 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CREB3L2-associated genes across cancer lineages are CRYM-AS1, IL11, and SPG11. Each is linked with CREB3L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CREB3L2-to-partner and partner-to-CREB3L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CREB3L2 versus CRYM-AS1 in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CREB3L2→partner) and Y-score (partner→CREB3L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CRYM-AS1 →	+0.629	+0.591	.009	<.001	3	2
LSCC	IL11 →	+1.081	+0.975	.001	.002	3	2
BRCA	SPG11 →	-0.810	-0.477	<.001	.001	3	2
BRCA	ANOS1 →	-1.344	-0.501	.005	.005	3	2
BRCA	BRD8 →	-0.658	-0.455	<.001	.001	3	2
BRCA	TRIM23 →	-0.849	-0.433	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,474 associations by consensus.

CREB3L2 vs CRYM-AS1 — UCEC

Explore this scatter interactively →