CREB3L2-AS1

Across TCGA pan-cancer cohorts, CREB3L2-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated CREB3L2-AS1 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher CREB3L2-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CREB3L2-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and ESCA show a favorable association.

READ, LUAD, and LIHC are the cancer types where CREB3L2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	All	0.812	0.972	<.001	54	view →
LUAD	DFS	Quartile	All	0.840	0.595	.002	34	view →
LIHC	DFS	Tertile	III,IV	0.096	0.450	<.001	30	view →
ESCA	OS	Tertile	II,III,IV	0.587	0.318	.019	30	view →
LAML	DFS	Median	All	0.467	0.283	.006	28	view →
MESO	DFS	Tertile	IV	0.109	0.354	.027	18	view →
CESC	OS	Tertile	IV	0.744	0.248	.049	18	view →
ACC	OS	Tertile	IV	0.251	0.743	<.001	18	view →
SKCM	DFS	Tertile	IV	0.042	0.471	.003	9	view →
THYM	DFS	Tertile	II,III,IV	0.406	0.757	.049	9	view →
PCPG	OS	Tertile	All	0.944	1.000	.045	6	view →
THCA	DFS	Tertile	IV	0.492	0.904	.006	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

CREB3L2-AS1–READ (OS)

Open the READ breakdown →