CREB3L2-AS1

Across TCGA pan-cancer cohorts, CREB3L2-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of CREB3L2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CREB3L2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CREB3L2-AS1 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KICH, LIHC, and BRCA are the cancer types where CREB3L2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CREB3L2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.131	.002	3	view →
LIHC	All	All	+0.025	.014	3	view →
BRCA	All	III,IV	−0.083	.044	2	view →
THCA	All	All	−0.073	.008	2	view →
STAD	All	IV	−0.140	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

CREB3L2-AS1–KICH

Open the KICH breakdown →