CREB1

Across TCGA cell cohorts, CREB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,628 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CREB1-associated GO terms across cancer lineages are Response to dehydroepiandrosterone, Regulation of RNA polymerase II transcription preinitiation complex assembly, and Response to hypobaric hypoxia. Each is linked with CREB1 in more than 19 cancer types. Because this analysis shows association rather than direction, both CREB1-to-partner and partner-to-CREB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to dehydroepiandrosterone grouped by CREB1-low versus CREB1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CREB1→partner) and Y-score (partner→CREB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Response to dehydroepiandrosterone →	+0.317	+1.648	<.001	<.001	3	20
BONE	Regulation of RNA polymerase II transcription preinitiation complex assembly →	+0.165	+1.191	<.001	<.001	3	18
URINARY_TRACT	Response to hypobaric hypoxia →	+0.170	+1.134	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA-templated transcription initiation →	+0.053	+0.901	<.001	<.001	2	18
BONE	Positive regulation of RNA polymerase II transcription preinitiation complex assembly →	+0.196	+1.065	<.001	<.001	3	17
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.083	+0.901	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,628 associations by consensus.

Response to dehydroepiandrosterone by CREB1 expression — OESOPHAGUS

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