CRB2

Across TCGA patient cohorts, CRB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,814 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CRB2-associated proteins across cancer lineages are RCOR3, WNK2, and ZNF219_S114. Each is linked with CRB2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CRB2-to-partner and partner-to-CRB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRB2 versus RCOR3 in HNSC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRB2→partner) and Y-score (partner→CRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RCOR3 →	+0.294	+0.447	<.001	<.001	3	4
HNSC	WNK2 →	+0.574	+0.437	<.001	<.001	3	3
HNSC	ZNF219_S114 →	+0.875	+0.474	<.001	.003	3	3
OV	RPL5 →	-0.141	-0.880	.007	.003	3	3
PDAC	SEMA4D →	+0.271	+0.239	<.001	.001	3	3
HNSC	GABPA →	+0.238	+0.463	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,814 associations by consensus.

CRB2 vs RCOR3 — HNSC

Explore this scatter interactively →