CRB2

Across TCGA patient cohorts, CRB2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,263 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRB2-associated genes across cancer lineages are RSPH14, SLC11A2, and PLAT. Each is linked with CRB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRB2-to-partner and partner-to-CRB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRB2 versus RSPH14 in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRB2→partner) and Y-score (partner→CRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RSPH14 →	+0.660	+0.414	<.001	<.001	3	2
OV	SLC11A2 →	-1.077	-1.071	.001	.004	3	2
BRCA	PLAT →	+3.038	+1.718	<.001	.004	3	2
BRCA	ARMC6 →	-0.708	-1.450	.004	.005	3	2
HNSC	CARS1 →	-0.529	-0.654	<.001	.005	3	2
GBM	CDKN1A →	+0.939	+0.376	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,263 associations by consensus.

CRB2 vs RSPH14 — GBM

Explore this scatter interactively →