CRB2

Across TCGA cell cohorts, CRB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,408 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CRB2-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Regulatory ncRNA-mediated gene silencing, and Nuclear-transcribed mRNA catabolic process. Each is linked with CRB2 in more than 10 cancer types. Because this analysis shows association rather than direction, both CRB2-to-partner and partner-to-CRB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by CRB2-low versus CRB2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRB2→partner) and Y-score (partner→CRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of gene expression, epigenetic →	+0.053	+1.056	.002	.004	2	11
BONE	Regulatory ncRNA-mediated gene silencing →	+0.078	+0.413	<.001	.008	3	9
BONE	Nuclear-transcribed mRNA catabolic process →	+0.077	+0.601	<.001	.001	3	8
BLOOD_Lymphoma	Positive regulation of double-strand break repair →	+0.061	+0.408	<.001	<.001	3	8
OVARY	Negative regulation of myoblast fusion →	+0.111	+1.503	<.001	<.001	3	8
OVARY	Negative regulation of RNA catabolic process →	+0.033	+1.329	.002	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,408 associations by consensus.

Negative regulation of gene expression, epigenetic by CRB2 expression — OVARY

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