CRADD

Across TCGA patient cohorts, CRADD RNA expression is significantly associated with the protein abundance of many other proteins, with 11,127 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CRADD-associated proteins across cancer lineages are SART3, THEMIS2, and SLTM. Each is linked with CRADD in more than 4 cancer types. Because this analysis shows association rather than direction, both CRADD-to-partner and partner-to-CRADD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRADD versus SART3 in LSCC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRADD→partner) and Y-score (partner→CRADD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SART3 →	+0.313	+0.525	<.001	<.001	3	5
UCEC	THEMIS2 →	-0.414	-0.435	.001	.004	3	5
BRCA	SLTM →	+0.312	+0.378	.001	.005	3	4
GBM	HSPA5 →	-0.418	-0.486	<.001	<.001	3	4
LSCC	ARHGAP9_S475 →	-0.592	-0.330	.001	.008	3	4
CCRCC	ARPC4 →	-0.351	-0.550	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,127 associations by consensus.

CRADD vs SART3 — LSCC

Explore this scatter interactively →