CRADD

Across TCGA cell cohorts, CRADD RNA expression is significantly associated with the go_rna of many other GO terms, with 2,146 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CRADD-associated GO terms across cancer lineages are Cold acclimation, Protein linear polyubiquitination, and Blood coagulation, intrinsic pathway. Each is linked with CRADD in more than 7 cancer types. Because this analysis shows association rather than direction, both CRADD-to-partner and partner-to-CRADD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cold acclimation grouped by CRADD-low versus CRADD-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRADD→partner) and Y-score (partner→CRADD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Cold acclimation →	+0.243	+1.234	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Protein linear polyubiquitination →	-0.124	-0.846	.009	.004	3	6
BREAST	Blood coagulation, intrinsic pathway →	-0.299	-0.984	<.001	<.001	3	6
CNS	MAPK cascade →	+0.031	+0.454	.002	.002	3	6
LUNG_NSCLC_LUAD	Amino sugar metabolic process →	+0.081	+0.608	<.001	<.001	3	6
LARGE_INTESTINE	Adiponectin-activated signaling pathway →	+0.074	+0.616	.001	.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,146 associations by consensus.

Cold acclimation by CRADD expression — PANCREAS

Explore this box plot interactively →