CR2

Across TCGA patient cohorts, CR2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,697 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CR2-associated genes across cancer lineages are SELP, ACKR1, and PIM2. Each is linked with CR2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CR2-to-partner and partner-to-CR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CR2 versus SELP in PDAC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CR2→partner) and Y-score (partner→CR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SELP →	+1.117	+1.011	.001	<.001	3	5
PDAC	ACKR1 →	+1.823	+0.964	<.001	<.001	3	5
HNSC	PIM2 →	+1.091	+0.719	.005	.006	3	4
BRCA	IL18RAP →	+1.026	+0.747	.001	.004	3	4
HNSC	KLHL6 →	+0.853	+0.722	.003	.002	3	4
HNSC	IGHD3-3 →	+2.045	+1.020	.002	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,697 associations by consensus.

CR2 vs SELP — PDAC

Explore this scatter interactively →