Across TCGA patient cohorts, CR1 protein abundance is significantly associated with the protein abundance of many other proteins, with 16,794 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CR1-associated proteins across cancer lineages are CEACAM8, FCN1, and MMP8. Each is linked with CR1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CR1-to-partner and partner-to-CR1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CR1→partner) and Y-score (partner→CR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CEACAM8 →	+2.211	+0.885	<.001	.001	2	8
GBM	FCN1 →	+2.080	+1.384	<.001	<.001	3	7
GBM	MMP8 →	+2.178	+1.400	<.001	<.001	3	7
COAD	CYBA →	+0.932	+1.127	.001	<.001	3	7
GBM	ARG1 →	+1.485	+1.378	<.001	<.001	3	6
PDAC	FGR →	+1.707	+0.866	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,794 associations by consensus.

Exploration

CR1 survival (RNA) · tumor vs normal (RNA) · all CR1 data types