CPZ

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CPZ RNA expression is significantly associated with the protein abundance of many other proteins, with 11,963 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CPZ-associated proteins across cancer lineages are PCOLCE, CNN2, and CDH11. Each is linked with CPZ in more than 7 cancer types. Because this analysis shows association rather than direction, both CPZ-to-partner and partner-to-CPZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPZ versus PCOLCE in UCEC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CPZ→partner) and Y-score (partner→CPZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPCOLCE →+0.692+0.652<.001<.00138
GBMCNN2 →+0.712+0.326.002.00638
OVCDH11 →+0.577+0.361<.001<.00137
LSCCCOL3A1 →+0.622+0.269<.001<.00137
LSCCFAP →+0.956+0.484<.001<.00137
UCECGSN →+0.576+0.558<.001.00337
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,963 associations by consensus.

CPZ vs PCOLCE — UCEC

Per-sample scatter of CPZ vs PCOLCE in UCEC (Pearson r = 0.43).

Explore this scatter interactively →

Exploration