CPZ

Across TCGA patient cohorts, CPZ protein abundance is significantly associated with the RNA expression of many other genes, with 12,563 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CPZ-associated genes across cancer lineages are MSC, TIMP3, and NALCN. Each is linked with CPZ in more than 6 cancer types. Because this analysis shows association rather than direction, both CPZ-to-partner and partner-to-CPZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPZ versus MSC in OV, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPZ→partner) and Y-score (partner→CPZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MSC →	+1.197	+0.609	<.001	<.001	3	7
OV	TIMP3 →	+1.876	+0.546	<.001	<.001	3	7
OV	NALCN →	+0.574	+0.518	<.001	<.001	3	7
OV	CCN4 →	+1.657	+0.674	<.001	<.001	3	7
OV	AEBP1 →	+2.150	+0.695	<.001	<.001	3	7
OV	ASPN →	+2.615	+0.563	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,563 associations by consensus.

CPZ vs MSC — OV

Explore this scatter interactively →