CPZ

Across TCGA cell cohorts, CPZ RNA expression is significantly associated with the go_rna of many other GO terms, with 3,402 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CPZ-associated GO terms across cancer lineages are Regulation of endothelial cell migration, Arp2/3 complex-mediated actin nucleation, and Negative regulation of cell adhesion. Each is linked with CPZ in more than 10 cancer types. Because this analysis shows association rather than direction, both CPZ-to-partner and partner-to-CPZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of endothelial cell migration grouped by CPZ-low versus CPZ-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPZ→partner) and Y-score (partner→CPZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of endothelial cell migration →	+0.078	+2.729	<.001	<.001	3	11
BONE	Arp2/3 complex-mediated actin nucleation →	+0.124	+2.479	<.001	.006	3	11
URINARY_TRACT	Negative regulation of cell adhesion →	+0.082	+2.993	.001	.006	3	10
URINARY_TRACT	Negative regulation of response to endoplasmic reticulum stress →	+0.117	+2.264	<.001	.009	3	10
BONE	Regulation of intracellular transport →	+0.044	+1.881	.002	<.001	3	10
BONE	Vesicle-mediated transport to the plasma membrane →	+0.097	+3.177	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,402 associations by consensus.

Regulation of endothelial cell migration by CPZ expression — BONE

Explore this box plot interactively →