CPZ

Across TCGA cell cohorts, CPZ mutation is significantly associated with the RNA expression of many other genes, with 195 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPZ-associated genes across cancer lineages are ASB17, PRY, and OR5G3. Each is linked with CPZ in more than 1 cancer types. Because this analysis shows association rather than direction, both CPZ-to-partner and partner-to-CPZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by CPZ-low versus CPZ-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPZ→partner) and Y-score (partner→CPZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ASB17 →	+0.017	+4.807	<.001	.003	3	2
BLOOD_Lymphoma	PRY →	+0.029	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	OR5G3 →	+0.044	+4.867	<.001	.009	3	1
STOMACH	KRTAP10-5 →	+0.036	+5.285	<.001	.003	3	1
LARGE_INTESTINE	CBY1 →	+0.702	+3.307	<.001	.003	3	1
LARGE_INTESTINE	CEP76 →	+0.623	+3.364	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 195 associations by consensus.

ASB17 by CPZ expression — OVARY

Explore this box plot interactively →