CPXCR1

Across TCGA patient cohorts, CPXCR1 mutation is significantly associated with the total protein of many other genes, with 56 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPXCR1-associated genes across cancer lineages are ASNS, TIGAR, and Cyclin-E1. Each is linked with CPXCR1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CPXCR1-to-partner and partner-to-CPXCR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by CPXCR1-low versus CPXCR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPXCR1→partner) and Y-score (partner→CPXCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.612	+2.523	<.001	<.001	3	5
UCEC	TIGAR →	+0.140	+1.541	.006	.009	3	3
COAD	Cyclin-E1 →	+0.262	+2.123	.007	.010	3	3
LUSC	PDK1_pS241 →	-0.136	-3.169	.046	.018	3	2
UCEC	Cyclin-B1 →	+0.782	+3.000	<.001	<.001	3	2
UCEC	JNK_pT183_Y185 →	-0.153	-1.906	.007	.015	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

ASNS by CPXCR1 expression — UCEC

Explore this box plot interactively →