CPXCR1

Across TCGA pan-cancer cohorts, CPXCR1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated CPXCR1 data layer compared with 7 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CPXCR1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CPXCR1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and CESC show a favorable association.

KIRC, THYM, and BLCA are the cancer types where CPXCR1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.761	0.889	<.001	144	view →
THYM	DFS	Tertile	All	0.374	0.791	<.001	87	view →
BLCA	DFS	Tertile	III,IV	0.300	0.511	<.001	72	view →
ESCA	OS	Tertile	All	0.838	0.636	.003	66	view →
MESO	OS	Tertile	All	0.142	0.674	<.001	51	view →
OV	DFS	Quartile	II,III,IV	0.311	0.402	.009	44	view →
CESC	DFS	Tertile	II,III,IV	0.885	0.648	.015	24	view →
UCEC	OS	Tertile	IV	0.485	0.806	.015	24	view →
ACC	DFS	Quartile	All	0.581	0.832	.012	19	view →
PAAD	DFS	Tertile	II,III,IV	0.060	0.439	<.001	18	view →
KICH	DFS	Tertile	II,III,IV	0.529	0.871	.023	18	view →
LUAD	OS	Tertile	All	0.748	0.650	.021	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

CPXCR1–KIRC (OS)

Open the KIRC breakdown →