CPXCR1

Across TCGA cell cohorts, CPXCR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 666 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CPXCR1-associated GO terms across cancer lineages are Negative regulation of lymphocyte differentiation, Negative regulation of T cell differentiation, and Defense response to virus. Each is linked with CPXCR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CPXCR1-to-partner and partner-to-CPXCR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of lymphocyte differentiation grouped by CPXCR1-low versus CPXCR1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPXCR1→partner) and Y-score (partner→CPXCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Negative regulation of lymphocyte differentiation →	+0.062	+0.068	<.001	.008	3	7
CNS	Negative regulation of T cell differentiation →	+0.083	+0.089	<.001	<.001	3	6
CNS	Defense response to virus →	+0.062	+0.086	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Regulation of regulatory T cell differentiation →	+0.067	+0.022	.005	.003	3	5
CNS	CD8-positive, alpha-beta T cell homeostasis →	+0.102	+0.085	<.001	<.001	3	4
CNS	Negative regulation of response to biotic stimulus →	+0.055	+0.093	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 666 associations by consensus.

Negative regulation of lymphocyte differentiation by CPXCR1 expression — CNS

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