CPT1C

Across TCGA cell cohorts, CPT1C mutation is significantly associated with the RNA expression of many other genes, with 662 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CPT1C-associated genes across cancer lineages are B3GNT4, SLC25A51, and FEM1A. Each is linked with CPT1C in more than 1 cancer types. Because this analysis shows association rather than direction, both CPT1C-to-partner and partner-to-CPT1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B3GNT4 grouped by CPT1C-low versus CPT1C-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPT1C→partner) and Y-score (partner→CPT1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	B3GNT4 →	+0.350	+3.489	.003	.001	3	2
LARGE_INTESTINE	SLC25A51 →	+0.841	+3.459	<.001	<.001	3	2
LARGE_INTESTINE	FEM1A →	+0.731	+3.628	<.001	<.001	3	2
LARGE_INTESTINE	SGCB →	+0.973	+3.628	.001	<.001	3	2
LARGE_INTESTINE	FAM160A1 →	+0.712	+3.628	.005	<.001	3	2
LARGE_INTESTINE	E2F2 →	+0.977	+3.628	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 662 associations by consensus.

B3GNT4 by CPT1C expression — BLOOD_Leukemia

Explore this box plot interactively →