CPT1C

Across TCGA pan-cancer cohorts, CPT1C RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated CPT1C data layer compared with 5 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher CPT1C RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CPT1C expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

KIRP, BLCA, and UVM are the cancer types where CPT1C RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.546	0.807	<.001	153	view →
BLCA	DFS	Median	All	0.270	0.417	<.001	130	view →
UVM	OS	Median	All	0.420	0.836	<.001	81	view →
STAD	OS	Tertile	All	0.386	0.743	.001	76	view →
ACC	DFS	Quartile	All	0.211	0.671	<.001	73	view →
MESO	OS	Tertile	All	0.249	0.495	<.001	61	view →
HNSC	OS	Median	II,III,IV	0.732	0.606	.005	53	view →
COAD	DFS	Quartile	All	0.412	0.639	<.001	47	view →
PAAD	DFS	Tertile	All	0.452	0.196	<.001	35	view →
UCEC	DFS	Tertile	All	0.500	0.688	.003	12	view →
LUSC	DFS	Median	III,IV	0.413	0.846	.008	12	view →
KIRC	DFS	Quartile	II,III,IV	0.387	0.657	.009	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

CPT1C–KIRP (OS)

Open the KIRP breakdown →