CPSF7

Across TCGA patient cohorts, CPSF7 mutation is significantly associated with the RNA expression of many other genes, with 2,888 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CPSF7-associated genes across cancer lineages are RN7SL248P, ERHP2, and RNU6-1050P. Each is linked with CPSF7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CPSF7-to-partner and partner-to-CPSF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by CPSF7-low versus CPSF7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPSF7→partner) and Y-score (partner→CPSF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.053	+2.985	<.001	.006	3	2
COAD	ERHP2 →	+0.259	+5.003	<.001	.004	3	2
SKCM	RNU6-1050P →	+0.361	+3.993	<.001	.005	3	2
UCEC	RNU6-601P →	+0.126	+2.845	<.001	.009	3	2
UCEC	MTATP6P21 →	+0.207	+1.774	<.001	.009	3	2
COAD	SYPL1P1 →	+0.111	+4.693	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,888 associations by consensus.

RN7SL248P by CPSF7 expression — UCEC

Explore this box plot interactively →