CPSF4

Across TCGA patient cohorts, CPSF4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,259 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CPSF4-associated proteins across cancer lineages are GTF2I, MEPCE, and BUD31. Each is linked with CPSF4 in more than 8 cancer types. Because this analysis shows association rather than direction, both CPSF4-to-partner and partner-to-CPSF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPSF4 versus GTF2I in HNSC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CPSF4→partner) and Y-score (partner→CPSF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GTF2I →	+0.486	+0.775	<.001	<.001	3	9
LSCC	MEPCE →	+0.404	+0.695	<.001	<.001	3	9
OV	BUD31 →	+0.376	+0.528	<.001	<.001	3	8
LSCC	PUS7 →	+0.595	+0.675	<.001	<.001	3	8
OV	PDAP1 →	+0.439	+0.533	<.001	.001	3	7
LUAD	HSPA14 →	+0.315	+0.489	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,259 associations by consensus.

CPSF4 vs GTF2I — HNSC

Explore this scatter interactively →