CPSF4

Across TCGA cell cohorts, CPSF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,997 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CPSF4-associated GO terms across cancer lineages are Pre-mRNA catabolic process, RNA localization, and Positive regulation of double-strand break repair via homologous recombination. Each is linked with CPSF4 in more than 17 cancer types. Because this analysis shows association rather than direction, both CPSF4-to-partner and partner-to-CPSF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by CPSF4-low versus CPSF4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPSF4→partner) and Y-score (partner→CPSF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.200	+0.804	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	RNA localization →	+0.091	+1.462	<.001	<.001	3	15
BONE	Positive regulation of double-strand break repair via homologous recombination →	+0.083	+0.635	<.001	<.001	3	15
BONE	Positive regulation of DNA recombination →	+0.095	+0.683	<.001	<.001	3	14
SOFT_TISSUE	RNA export from nucleus →	+0.116	+1.211	<.001	<.001	3	14
BONE	Signal transduction in response to DNA damage →	+0.086	+0.731	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,997 associations by consensus.

Pre-mRNA catabolic process by CPSF4 expression — BONE

Explore this box plot interactively →