CPQ

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CPQ RNA expression is significantly associated with the protein abundance of many other proteins, with 18,854 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CPQ-associated proteins across cancer lineages are RSU1, ILK, and PRKG1. Each is linked with CPQ in more than 8 cancer types. Because this analysis shows association rather than direction, both CPQ-to-partner and partner-to-CPQ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPQ versus RSU1 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CPQ→partner) and Y-score (partner→CPQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRSU1 →+0.404+0.789<.001<.00139
OVILK →+0.460+0.683<.001<.00139
OVPRKG1 →+0.825+0.919<.001<.00138
UCECCAVIN1 →+0.914+0.933<.001<.00138
OVISLR →+0.878+0.721<.001<.00138
UCECLPP →+0.709+0.994<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,854 associations by consensus.

CPQ vs RSU1 — GBM

Per-sample scatter of CPQ vs RSU1 in GBM (Pearson r = 0.45).

Explore this scatter interactively →

Exploration