CPQ

Across TCGA cell cohorts, CPQ RNA expression is significantly associated with the go_rna of many other GO terms, with 5,805 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CPQ-associated GO terms across cancer lineages are Endoplasmic reticulum to Golgi vesicle-mediated transport, Golgi vesicle transport, and Macroautophagy. Each is linked with CPQ in more than 14 cancer types. Because this analysis shows association rather than direction, both CPQ-to-partner and partner-to-CPQ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to Golgi vesicle-mediated transport grouped by CPQ-low versus CPQ-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPQ→partner) and Y-score (partner→CPQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.104	+1.528	.001	.001	3	15
BONE	Golgi vesicle transport →	+0.062	+3.064	.002	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.071	+1.801	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Process utilizing autophagic mechanism →	+0.069	+1.551	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Autophagy →	+0.069	+1.551	<.001	<.001	3	13
BONE	Biological process involved in symbiotic interaction →	+0.100	+2.472	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,805 associations by consensus.

Endoplasmic reticulum to Golgi vesicle-mediated transport by CPQ expression — OESOPHAGUS

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